147 YC Biotech Startups

147 Y Combinator companies carry the Biotech tag in YC's own directory, across every batch since 2005. Each row shows what the company does, its batch, HQ and status, and links to its YC application reconstructed in the real form, so a founder building a Biotech startup can read how accepted companies answered the same questions.

Companies
147
Top industries
Healthcare, Industrials and B2B
Top locations
San Francisco, Boston and New York
YC top companies
3
147 reconstructed applications

Read the YC application of all 147 companies

  • Every company's YC application, reconstructed in the real form
  • Filter every batch by industry, country and team size
  • Then find the investors who fund startups like yours

The first 100 companies, top companies first

2
Notable Labs
Notable LabsTopPersonalized drug discovery for blood cancer.
Winter 2015Foster City, CAPublic
3
Pardes Biosciences
Pardes BiosciencesTopWe break viruses
Summer 2020San Francisco, CAPublic
6
20n
20nUsing AI to predict biochemistry for manufacturing and therapeutics
Winter 2015San Francisco, CAInactive
7
AbInitio Bio
AbInitio BioThe Intelligence layer for Drug Manufacturing
Spring 2026San Francisco, CAActive
9
Adventris Pharmaceuticals
Adventris PharmaceuticalsAdventris makes cancer vaccines
Winter 2023Baltimore, MDActive
10
Alga Biosciences
Alga BiosciencesWe stop cows from burping methane.
Winter 2022Berkeley, CAActive

That is 10 of 147.

Every company below has its YC application reconstructed in YC Insights. Create a free account to read them all.

Read all 147 applications
11
Alixia
AlixiaTargeting the Tumor Ecosystem to address cancer drug resistance.
Winter 2022San Francisco, CAActive
14
AminoAnalytica
AminoAnalyticaThe AI scientist for always-on biosecurity
Summer 2024London, United KingdomActive
15
Andson Biotech
Andson BiotechEmpowering Mass Spec for Biotech and Beyond
Winter 2022Atlanta, GAActive
17
Ansa Biotechnologies
Ansa BiotechnologiesNext-generation DNA synthesis using enzymes
Winter 2020Emeryville, CAActive
19
Anto Biosciences
Anto BiosciencesA Foundation Model for Microbial Communities.
Fall 2025San Francisco, CAActive
21
Asher Bio
Asher BioWe build better immunotherapies
Summer 2019San Carlos, CAActive
22
Avro Life Science
Avro Life ScienceSkin patches for generic drug delivery.
Winter 2018Waterloo, ON, CanadaActive
24
Biocartesian
BiocartesianConverting biology into digital molecular maps
Summer 2024San Francisco, CAActive
25
Birch Biosciences
Birch BiosciencesWe recycle plastic using engineered enzymes
Summer 2022Portland, ORActive
26
BLUUMBIO
BLUUMBIOWe make bacteria and plants that clean up pollution.
Summer 2021San Francisco, CAActive
27
Bramante
BramanteLife sciences instrument and reagent manufacturing
Spring 2025Cambridge, MAActive
28
Brown Foods
Brown FoodsMaking 'REAL' Cow and Human Milk!
Winter 2022Boston, MAActive
30
Catena Biosciences
Catena BiosciencesUsing protein coupling to build new therapies
Summer 2021Berkeley, CAActive
33
Cisterna Biologics
Cisterna BiologicsHigh quality mRNA for therapeutic application
Summer 2022San Diego, CAActive
35
Convexia
ConvexiaThe world's first AI-maximalist pharma company
Summer 2025San Francisco, CAActive
36
Culture Biosciences
Culture BiosciencesWe grow cells for biotech companies.
Winter 2018South San Francisco, CAActive
38
Delineate
DelineateAgents for Accelerated Clinical Trial Design
Winter 2025Boston, MAActive
39
Diffuse Bio
Diffuse BioGenerative AI for protein design
Winter 2023San Carlos, CAActive
41
Engage Bio
Engage BioPotent, durable, and redosable non-viral genetic medicines
Winter 2022San Francisco, CAAcquired
46
Evolvere BioSciences
Evolvere BioSciencesMaking Next-Generation Antibiotics that Outpace Bacterial Evolution
Summer 2024Oxford, England, United KingdomActive
47
Excepgen
Excepgen
Winter 2019San Francisco, CAActive
48
Exin Therapeutics
Exin TherapeuticsAI drug discovery platform for neurotherapeutics
Winter 2025San Francisco, CAActive
49
Felix Biotechnology
Felix BiotechnologyWe’re creating programmable therapies
Winter 2020San Francisco, CAInactive
50
Frekil
FrekilRWE Generation in minutes
Spring 2025San Francisco, CAActive
52
Gamgee
GamgeeCuring cancer. Starting with dogs.
Summer 2026San Francisco, CAActive
54
General Proximity
General ProximityThe next generation of induced-proximity medicines.
Winter 2020San Francisco, CAActive
56
Gleam
GleamAutomating Data Entry for Clinical Trials
Summer 2023San Francisco, CAActive
57
Granza Bio
Granza BioReprogramming Immunity for Target-Specific Medicines
Winter 2024San Francisco, CAActive
58
Guardian Bio
Guardian BioDendritic cell-based platform for cancer therapy
Summer 2022Boston, MAActive
60
Halmos Labs
Halmos LabsMaximum information per experiment, minimum experiments per conclusion
Fall 2026Lund, Skåne County, SwedenActive
63
Hepatx
HepatxReplacing organ transplant with an infusion
Summer 2018Palo Alto, CAActive
64
HistoWiz
HistoWizAccelerating Histopathology for Cancer Research
Winter 2016Brooklyn, NYActive
65
HypaHub
HypaHubA Cloud-Based Bioinformatics and AI Platform
Winter 2022Sunnyvale, CAAcquired
66
Illume Labs
Illume Labs24/7 Personal Health & Longevity Companion
Summer 2026San Francisco, CAActive
67
Immunity Project
Immunity ProjectThe free HIV vaccine.
Winter 2014San Francisco, CAActive
68
InnaMed
InnaMedAt-home blood testing: measure + analyze + enhance.
Winter 2017San Francisco, CAInactive
69
Invert
InvertData analytics software for biomanufacturing.
Winter 2022San Francisco, CAActive
70
Invitris
InvitrisCreating new protein-based drugs at scale
Winter 2023Munich, BY, GermanyActive
71
Isabl
IsablCancer tests based on whole genome and transcriptome data.
Winter 2020New York, NYActive
75
Lamin
LaminOpen data lakehouse for biology
Summer 2022Active
76
Lavo Life Sciences
Lavo Life SciencesAI for drug formulation
Winter 2023Inactive
77
Ligo Biosciences
Ligo BiosciencesEnzyme design models.
Summer 2024San Francisco, CAActive
78
Living Carbon
Living Carbonmaximizing biomass on low quality land
Winter 2020San Francisco, CAActive
79
Loop Genomics
Loop GenomicsNovel long-read DNA sequencing technology
Winter 2016San Jose, CAAcquired
82
Maven Bio
Maven BioThe AI Platform for Life Sciences Intelligence
Summer 2023Boston, MAActive
83
Medium Biosciences
Medium BiosciencesAI-designed Affinity Reagents
Summer 2021San Francisco, CAActive
84
Micro Meat
Micro MeatTechnologies for scaling up cultured/clean meat production
Summer 2021Monterrey, N.L., MexicoInactive
85
Mindstate Design Labs
Mindstate Design LabsClinical-stage AI neuroengineering platform
Summer 2021San Francisco, CAActive
86
Miracle
MiracleAccelerate clinical trials with real-time, actionable insights
Winter 2023San Francisco, CAActive
87
Modulari-T
Modulari-TWe teach your immune system to attack and cure cancer
Winter 2023Montreal, QC, CanadaActive
88
Molagri
MolagriResistance free pesticides.
Summer 2026Toronto, ON, CanadaActive
89
Mytos
MytosRobotic human cell manufacturing
Summer 2018London, England, United KingdomActive
90
Nanograb
NanograbDeliver genes to any cell with AI
Summer 2023San Francisco, CAActive
91
Nephrogen
NephrogenCurative genetic medicines for kidney diseases
Summer 2020New York, NYActive
92
Neuromorphic
NeuromorphicBuilding robots to automate wetlabs
Summer 2026San Francisco, CAActive
93
Numen
NumenEngineering a future without cancer deaths.
Summer 2023San Francisco, CAActive
94
Numerion Labs
Numerion LabsArtificial intelligence for drug discovery.
Winter 2015San Francisco, CAActive
95
Ochre Bio
Ochre BioRNA medicines for liver diseases
Winter 2020Oxford, England, United KingdomActive
97
One Codex
One CodexData platform for metagenomics and the microbiome.
Summer 2014Boston, MAAcquired
98
Opentrons
OpentronsWe make robots for biologists.
Winter 2016New York, NYActive
99
Origami Therapeutics, Inc.
Origami Therapeutics, Inc.Oral drugs to halt neurodegeneration
Winter 2022San Diego, CAActive

The other 47 companies

Every remaining company in this list, A to Z. Each link opens the company's public page.

Applying to YC? Study these applications first.

YC Insights holds the reconstructed application of every company on this page, filterable by batch, industry and country, next to 60,000+ investors who fund startups like yours.

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About this list

This list is part of Round Funded, an investor database and outreach platform for founders. It covers 60,000+ active VCs, angels, family offices and accelerators with verified contacts, lets you send pitches from your own Gmail, and includes a free Data Room for your raise. How this data is built.

Frequently Asked Questions

How many Y Combinator companies are in tagged Biotech?

This directory lists 147 YC companies in tagged Biotech, out of 6,207 across every batch since 2005. The count updates when the directory is refreshed, and every one of them is on this page with a link to its public profile.

Are the YC applications on these pages real?

No. YC keeps submitted applications private. Every application linked from this list is a reconstruction: the real YC form questions, answered from the company's public data. The Company section is free on each page; the rest opens in YC Insights.

Which companies on this page are best known?

Benchling, Notable Labs and Pardes Biosciences lead the table above. YC marks 3 of the 147 companies here as top companies, its own list of the highest-valued and highest-revenue alumni.

How do I use this list when applying to YC?

Pick five companies on this page whose product is closest to yours, read their reconstructed applications side by side in YC Insights, and note how each answers the same question. Then write your own answers to that standard.

Where does this data come from?

From YC's public company directory, refreshed by batch, with each company's status, industry and location as YC reports them. Round Funded adds the reconstructed application and the founder profiles; nothing private is published.

What is Round Funded?

Round Funded is an investor database and outreach platform for startup founders. It lists 60,000+ active investors with verified contacts, filtered to recent investment activity, and lets founders send personalized pitches from their own Gmail, track replies, and share a free Data Room. Round+ starts at $99 per month with a 3-day trial.