35 Startup Investors in San Diego (2026)
67 investor organizations in San Diego are in the Round Funded catalog: venture capital firms, accelerators and incubators. Below are the top 35 by investments on record: what each one backs, where it is based, how many startups it has invested in, and a way to reach the team behind each once you sign up.
- Investors in the catalog
- 67 in San Diego
- Top sectors
- Healthcare & Biotech, SaaS & Enterprise, and Artificial Intelligence
- Median investments
- 16 investments
- This list
- Updated for 2026
Reach the teams at all 35 investors
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The top 35 startup investors in San Diego, by investments on record
Qualcomm VenturesQualcomm Ventures is a global investor that assists entrepreneurs in creating revolutionary businesses.San DiegoArtificial IntelligenceAutomotive & EVIoT & Connected Devices500 investments
Nex Cubed Digital HealthNex Cubed Digital Health is a customized, semi-remote, startup accelerator that connects talented founders with healthcare experts.San DiegoDigital Health & HealthTechHealthcare & BiotechArtificial Intelligence300 investments
StartRStartR is a nonprofit accelerator for Rady School of Management students and alumni.San Diego300 investments
HarpoonHarpoon is an early-stage venture capital that specializes in finance and investment management.San DiegoArtificial IntelligenceCybersecuritySaaS & Enterprise65 investments
Shepherd VenturesShepherd Ventures was founded in 2001 and is headquartered in San Diego, part of Southern California's Tech Coast, with easy access toSan DiegoSaaS & EnterpriseDigital Health & HealthTechFintech30 investments
Moshulu Enterprise PartnersMoshulu Enterprise Partners is a cessionary company of architect businesses.San DiegoHealthcare & BiotechArtificial IntelligenceFintech25 investments
Suncoast VenturesSuncoast Ventures is a venture capital firm that provides mentorship and support to companies, with a focus on healthcare innovation.San DiegoHealthcare & BiotechDigital Health & HealthTechBiotech & Pharma21 investmentsThat is 10 of 35.
Every firm and program below has a contact in the catalog. Create a free account to see them all.
i2020 AcceleratorThe i2020 Accelerator will provide funding and resources to companies in the areas of inflammation, oncology, CNS, and infectious diseasesSan DiegoHealthcare & BiotechBiotech & PharmaArtificial Intelligence17 investments
FusionX VenturesFusionX Ventures is an early-stage investment fund focused on helping companies build the next generation of cloud-enabled Smart Machines.San DiegoHardware & Deep TechHealthcare & BiotechManufacturing & Industrial16 investments
TechAcq VenturesTechAcq Ventures is a California-based venture capital firm with offices in San Francisco, New York, and the Pacific Northwest.San DiegoHealthcare & BiotechClimate & EnergyFoodTech & Agriculture14 investments
Phase Two VenturesPhase Two Ventures invests in early-stage biotech startups, focusing on life science tools and computational biology.San DiegoHealthcare & BiotechBiotech & PharmaArtificial Intelligence11 investments
Rolling Thunder VenturesRolling Thunder Ventures invests in startups and supports early-stage companies focused on technology, innovation, and digital growth.San DiegoConsumer Goods (CPG)SaaS & EnterpriseTravel & Hospitality11 investments
Sutra VenturesSutra Ventures invests in early stage companies operating in the fintech, artificial intelligence and small business sectors.San DiegoArtificial IntelligenceSaaS & EnterpriseFintech7 investments
Launch FactoryLaunch factory is a start-up studio and investment firm that launches startup companiesSan DiegoArtificial IntelligenceSaaS & EnterpriseDeveloper Tools & Data4 investments
Simplexity Venture Studio FundSimplexity Venture Studio Fund is a is a Co-Founding Venture Studio.San DiegoFintechSaaS & EnterpriseDigital Health & HealthTech3 investments
The SwitchCase GroupThe SwitchCase Group is a partnership between a principal private investor and a small group of skilled technology entrepreneurs.San DiegoSaaS & EnterpriseConsumer & RetailGaming & Entertainment3 investments
Tioga IncubatorTioga Incubator supports startups in the finance industry, offering guidance and resources for business growth and community involvement.San DiegoHealthcare & BiotechMedTech & Medical DevicesFintech1 investments
Mindgruve VenturesA tech innovation company accelerating opportunities within mobile, social media and commerce.San DiegoConsumer Goods (CPG)Media & ContentE-commerce & D2C1 investments
EMCIFundEMCIFund is an oncology-focused venture capital fund that invests in US and EU-based cancer start-ups.San DiegoHealthcare & BiotechBiotech & PharmaMedTech & Medical Devices
Grantchester GroupGrantchester Group is an equity firm that invest in healthcare, energy, and industrials.San DiegoHealthcare & BiotechManufacturing & Industrial
Make N ModMake N Mod is a learning, design, and creation facility combined with a business incubator.San DiegoConsumer & RetailManufacturing & IndustrialEdTech
Pitch the investors that back startups like yours.
Round Funded holds 67 investor organizations in San Diego next to 60,000+ investors worldwide, with the contact to reach at each, and the outreach to do it from your own inbox.
How to find the right startup investors in San Diego
Start with focus, not fame: the stage each investor takes, the sectors it backs and how many startups it has funded. Shortlist the VC firms that write checks at your stage, add the accelerators and incubators that take companies like yours, and write to each with your traction and your ask in the first three lines. An investor with many deals in your sector is a better first email than a famous name with none.
About this list
This list is part of Round Funded, an investor database and outreach platform for founders. It covers 60,000+ active VCs, angels, family offices and accelerators with verified contacts, lets you send pitches from your own Gmail, and includes a free Data Room for your raise. How this data is built.
Frequently Asked Questions
How many startup investors are there in San Diego?
The Round Funded catalog lists 67 investor organizations in San Diego: venture capital firms, accelerators and incubators. This page shows the top 35 by investments on record; the count updates as the catalog is refreshed.
How is this list ranked?
By the number of investments on record for each firm or program, then by how complete its profile is. It is a catalog ranking, not an editorial one: an investor with many recorded deals sits above a famous name with few.
How do I pitch startup investors in San Diego?
Open each investor's profile for its stage and sector focus first, then pitch the ones that match. VC firms take cold emails with traction up top; accelerators and incubators take applications through their own site. Sign up to see the contact behind each investor and reach them from your own Gmail.
Are these investors still active?
The catalog is refreshed continuously and each profile shows the investments on record. Check an investor's latest deals on its profile before you write, since focus and fund cycles change during the year.
What is Round Funded?
Round Funded is an investor database and outreach platform for startup founders. It lists 60,000+ active investors with verified contacts, filtered to recent investment activity, and lets founders send personalized pitches from their own Gmail, track replies, and share a free Data Room. Round+ starts at $99 per month with a 3-day trial.