35 VC Firms in San Diego Investing in Startups (2026)

52 active venture capital firms in San Diego are in the Round Funded catalog. Below are the top 35 by investments on record: what each fund backs, where it sits, how many deals it has done, and a way to reach the partner behind every name once you sign up.

Last updated October 25, 2026

Firms in the catalog: 52 in San Diego
Top sectors: SaaS & Enterprise, Artificial Intelligence, and Healthcare & Biotech
Median investments: 14 deals
This list: Investing in 2026

52 firms in the catalog

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The top 35 VC firms in San Diego, by investments on record

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Qualcomm VenturesQualcomm Ventures is a global investor that assists entrepreneurs in creating revolutionary businesses.San DiegoArtificial IntelligenceAutomotive & EVIoT & Connected Devices500 deals

HarpoonHarpoon is an early-stage venture capital that specializes in finance and investment management.San DiegoArtificial IntelligenceCybersecuritySaaS & Enterprise65 deals

Shepherd VenturesShepherd Ventures was founded in 2001 and is headquartered in San Diego, part of Southern California's Tech Coast, with easy access toSan DiegoSaaS & EnterpriseDigital Health & HealthTechFintech30 deals

Moshulu Enterprise PartnersMoshulu Enterprise Partners is a cessionary company of architect businesses.San DiegoHealthcare & BiotechArtificial IntelligenceFintech25 deals

Spark Growth VenturesMid/Late Stage Tech VC, Micro PESan Diego24 deals

Suncoast VenturesSuncoast Ventures is a venture capital firm that provides mentorship and support to companies, with a focus on healthcare innovation.San DiegoHealthcare & BiotechDigital Health & HealthTechBiotech & Pharma21 deals

FusionX VenturesFusionX Ventures is an early-stage investment fund focused on helping companies build the next generation of cloud-enabled Smart Machines.San DiegoHardware & Deep TechHealthcare & BiotechManufacturing & Industrial16 deals

TechAcq VenturesTechAcq Ventures is a California-based venture capital firm with offices in San Francisco, New York, and the Pacific Northwest.San DiegoHealthcare & BiotechClimate & EnergyFoodTech & Agriculture14 deals

Phase Two VenturesPhase Two Ventures invests in early-stage biotech startups, focusing on life science tools and computational biology.San DiegoHealthcare & BiotechBiotech & PharmaArtificial Intelligence11 deals

Rolling Thunder VenturesRolling Thunder Ventures invests in startups and supports early-stage companies focused on technology, innovation, and digital growth.San DiegoConsumer Goods (CPG)SaaS & EnterpriseTravel & Hospitality11 deals

That is 10 of 35.

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Sutra VenturesSutra Ventures invests in early stage companies operating in the fintech, artificial intelligence and small business sectors.San DiegoArtificial IntelligenceSaaS & EnterpriseFintech7 deals

Pelagos VenturesPelagos Ventures leverages capital and collaboration to drive growth and reduce risk in the finance industry.San Diego5 deals

Founders First Capital PartnersFounders First Capital Partners is a financial services company that offers advisory services.San Diego4 deals

Simplexity Venture Studio FundSimplexity Venture Studio Fund is a is a Co-Founding Venture Studio.San DiegoFintechSaaS & EnterpriseDigital Health & HealthTech3 deals

The SwitchCase GroupThe SwitchCase Group is a partnership between a principal private investor and a small group of skilled technology entrepreneurs.San DiegoSaaS & EnterpriseConsumer & RetailGaming & Entertainment3 deals

Mindgruve VenturesA tech innovation company accelerating opportunities within mobile, social media and commerce.San DiegoConsumer Goods (CPG)Media & ContentE-commerce & D2C1 deals

EMCIFundEMCIFund is an oncology-focused venture capital fund that invests in US and EU-based cancer start-ups.San DiegoHealthcare & BiotechBiotech & PharmaMedTech & Medical Devices

Grantchester GroupGrantchester Group is an equity firm that invest in healthcare, energy, and industrials.San DiegoHealthcare & BiotechManufacturing & Industrial

Moore Venture PartnersStage Agnostic | Technology + Life ScienceSan Diego

Poppy CapitalPoppy Capital is an investment firm that focuses on the acquisition, growth, and management of businesses of lower middle-market companies.San DiegoImpact & Social Enterprise

Summit Water Capital AdvisorsSummit Water has an unrivaled, 30-year focus on investment strategies into the global water industry.San Diego

Torrey Pines BankTorrey Pines Bank is a bank that offers business loans, banking, and financial services.San Diego

2020 Venture Partners2020 Venture Partners provides technology and operations consulting to private equity firms and venture capitalists.San Diego

Berg Capital MarketsBerg Capital Markets focuses on analytics, venture capital, private equity, investor marketing, and relations of various sectors.San DiegoDeveloper Tools & Data

BlueSky CapitalBlueSky Capital is a financial company that provides investments solutions for telecom, energy, and tech sector.San Diego

Boulder FieldBoulder Field is a venture capital firm that is looking to acquire and grow one tech-enabled company.San Diego

Costanzo CapitalCostanzo Capital is a private equity firm that offers angel investments and acquisition services.San Diego

CounterPoint Capital ManagementCounterpoint Asset Management provides investment management services with a focus on absolute-return strategies.San Diego

Digital KarmaDigital Karma is an investment and investment advisory services firm focused on early stage digital media companies.San DiegoFintech

Executive VenturesExecutive Ventures provides investors with a diverse portfolio of investment alternatives that deliver high returns on your investment.San DiegoArtificial IntelligenceDeveloper Tools & DataIoT & Connected Devices

Fund AthenaFund Athena is the world's first SEC RegA+ marketplace for main street investors to invest growth funds in businesses.San DiegoMarketplace

Gatti GroupGatti Group specializes in the fields of venture capital, market research, business planning and development services.San Diego

HillstoneHillstone is an investment company that focuses on investing capital in start-ups of AI and blockchain technology companies.San DiegoCrypto & Web3

Kay VenturesKay Ventures invests in diverse private companies, focusing on venture capital and private equity.San DiegoArtificial IntelligenceDeveloper Tools & DataSaaS & Enterprise

KDF VenturesKDF Ventures provides Investment, advice, and financial consulting for startup and nascent innovative companies.San Diego

Pitch the funds that back startups like yours.

Round Funded holds 52 active VC firms in San Diego next to 60,000+ investors worldwide, each with the partner to write to, and the outreach to do it from your own inbox.

Start with these 35 firms

How to pitch a VC firm in San Diego

Open the firm's profile first: its stage focus, the sectors it actually funds and the size of round it usually joins. Then write to the partner who covers your space, with the traction and the ask in the first three lines. A fund that has done many deals in your sector this year is a warmer lead than a famous name that has not.

About this list

This list is part of Round Funded, an investor database and outreach platform for founders. It covers 60,000+ active VCs, angels, family offices and accelerators with verified contacts, lets you send pitches from your own Gmail, and includes a free Data Room for your raise. How this data is built.

Frequently Asked Questions

How many VC firms are there in San Diego?

The Round Funded catalog lists 52 active venture capital firms in San Diego, after excluding banks, lenders, wealth managers, insurers and real-estate vehicles. This page shows the top 35 by investments on record; the count updates as the catalog is refreshed.

How is this list ranked?

By the number of investments on record for each firm, then by how complete its profile is. It is a catalog ranking, not an editorial one: a fund with many recorded deals sits above a famous name with few.

How do I get in touch with a VC firm in San Diego?

Every firm on this page links to its profile with stage and sector focus. Sign up to see the partner contact behind each firm and send your pitch from your own Gmail, with replies tracked on the Round Funded pipeline.

Are these firms actively investing?

The catalog is built from funds with recent investment activity and is re-checked continuously; each profile shows the investments on record. Read the firm's stage and sector focus before you write, since an active fund in the wrong sector is still a no.

What is Round Funded?

Round Funded is an investor database and outreach platform for startup founders. It lists 60,000+ active investors with verified contacts, filtered to recent investment activity, and lets founders send personalized pitches from their own Gmail, track replies, and share a free Data Room. Round+ starts at $99 per month with a 3-day trial.

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