Intersouth Partners
Intersouth Partners is a venture capital firm based in Durham, United States, focused on Seed to Series B startups in Healthcare & Biotech, SaaS & Enterprise, and Digital Health & HealthTech. This profile covers its focus and how founders can get in front of it in 2026.
- Investment focus
- Healthcare & BiotechSaaS & EnterpriseDigital Health & HealthTechBiotech & Pharma
- Investment stages
- SeedSeries ASeries B
- Location
- Durham, United States
- Team size
- 1-10
- Portfolio companies
- 100+
- Latest deal on record
- September 2024
About Intersouth Partners
Intersouth Partners is one of the most active and experienced venture funds in the Southeast, having invested in more than 100 private companies over the last three decades. Founded in 1985, Intersouth manages $780 million in seven venture capital limited partnerships, making it the largest venture capital fund in North Carolina and one of the largest in the Southeast.
Source: the organization's public company profile.
How to pitch Intersouth Partners
The founders who hear back from Intersouth Partners lead with traction and a clear ask that matches its stage, not a generic mass email. Build a targeted, verified list, write a personalized note, and track who opens it, all in one place.
Connect with Intersouth Partners
About this profile
This profile is part of Round Funded, an investor database and outreach platform for founders. It covers 60,000+ active VCs, angels, family offices and accelerators with verified contacts, lets you send pitches from your own Gmail, and includes a free Data Room for your raise. How this data is built.
Cite this page
Round Funded. "Intersouth Partners." Round Funded investor database, updated October 19, 2026.
Stable URL, it will not change: https://www.roundfunded.com/en/vc/intersouth-partners
Frequently Asked Questions
What does Intersouth Partners invest in?
Intersouth Partners focuses on Healthcare & Biotech, SaaS & Enterprise, Digital Health & HealthTech, and Biotech & Pharma. Match your sector and stage before reaching out, then find similar active investors on Round Funded.
What stage does Intersouth Partners invest at?
Intersouth Partners focuses on Seed to Series B rounds. Lead with traction that fits the stage when you reach out.
Is Intersouth Partners actively investing?
Yes. Round Funded's research found that Intersouth Partners has made a new investment or run a new cohort since 2024, and its latest deal on record is from September 2024. Reach out with a personalized pitch that fits its stage and focus, then track who opens it.
Where is Intersouth Partners based?
Intersouth Partners is based in Durham, United States. You can reach out from anywhere with a pitch that matches its focus.
How do I contact Intersouth Partners?
Unlock a verified email for Intersouth Partners and reach out with a personalized pitch on Round Funded. We show only deliverable contacts, so your outreach does not bounce.
What is Round Funded?
Round Funded is an investor database and outreach platform for startup founders. It lists 60,000+ active investors with verified contacts, filtered to recent investment activity, and lets founders send personalized pitches from their own Gmail, track replies, and share a free Data Room. Round+ starts at $99 per month with a 3-day trial.