Stephen Hoffman
Angel investor in San Mateo
San Mateo, California
Stephen Hoffman, Angel investor in San Mateo is an active investor based in San Mateo, California. This profile covers what Stephen Hoffman backs, at which stage, and how founders can reach out in 2026.
Dr. Stephen Hoffman serves as Board Member at Talphera. Dr. Hoffman is an Angel Investor. He Co-Founded and served as Managing Partner at Trekk Venture Partners. He served as a Board Member at Receptor. He served as a Board Member at Danforth Advisors and Palleon Pharmaceuticals. Dr. Hoffman has served as Chief Executive Officer and Director of Aerpio Pharmaceuticals, Inc. since December 2017. Earlier, he had been a Senior Advisor to PDL BioPharma, Inc. since February 2014. Earlier, he served as a managing director at Skyline Ventures, a venture capital firm, from May 2007 until February 2014. From January 2003 to March 2007, Dr. Hoffman was a general partner at TVM Capital, a venture capital firm. From 1994 to 2012, he served as President, Chief Executive Officer, and Director of Allos Therapeutics, a biopharmaceutical company; and served as Chairman of the Board from 2002 until its acquisition by Spectrum Pharmaceuticals in 2012. He served as Chairman at Apic Bio. He currently serves on the board of directors of Dicerna Pharmaceuticals, Inc. and Palleon Pharmaceuticals, Inc. Dr. Hoffman holds a Ph.D. in chemistry from Northwestern University and an M.D. from the University of Colorado, School of Medicine.
- Investor type
- Angel
- Stages
- Early Stage Venture
- Invests in
- Biotech & PharmaHealthcare & Biotech
- Location
- San Mateo, California
- Typical check
- $500K
- Past investments
- 16
Notable investments
Concert PharmaceuticalsAllos Therapeutics
Dicerna PharmaceuticalsProteon Therapeutics
Pionyr ImmunotherapeuticsKAI PharmaceuticalsPalleon PharmaceuticalsAcelRx Pharmaceuticals, Inc.
Collegium PharmaceuticalGenocea BiosciencesPDL BioPharmaBYOMass, Inc.How to reach Stephen Hoffman
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Round Funded. "Stephen Hoffman." Round Funded investor database, updated September 9, 2026.
Stable URL, it will not change: https://www.roundfunded.com/en/investor/stephen-hoffman-169461-7
Frequently Asked Questions
What does Stephen Hoffman invest in?
Stephen Hoffman invests in Biotech & Pharma and Healthcare & Biotech, typically at Early Stage Venture. Match your sector and stage, then reach out with a personalized pitch.
What stage does Stephen Hoffman invest at?
Stephen Hoffman typically invests at Early Stage Venture. Lead with traction that fits the stage when you reach out.
What is Stephen Hoffman's typical check size?
Stephen Hoffman typically writes checks around $500K. Use it as a signal for whether your raise fits their stage.
How do founders reach investors like this?
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