Cisterna Biologics YC 지원서

Summer 2022Active

Cisterna Biologics은(는) Summer 2022 배치에서 Healthcare 회사로 Y Combinator를 거쳤습니다. 아래에는 회사의 사업 내용, 창립자, 그리고 실제 YC 양식에 맞춰 재구성한 YC 지원서가 있습니다.

YC 배치: Summer 2022
산업: Healthcare
팀 규모: 2
상태: Active
출시됨: 2022

창업자

Hari BhaskaranFounder

Cisterna Biologics의 사업 내용

Founded in 2022 and based in San Diego, California, Cisterna Biologics is a technology company. It aims to solve some of the challenges currently facing the biotech industry to develop mRNA-based therapeutics - quality, quantity, longevity and cost of mRNA. As mRNA technology matures, it becomes imperative that these issues are solved so we can fully explore mRNA's endless possibilities as a therapeutic. Cisterna uses proprietary technologies to either remove a contaminant at its source or replace the source itself. For example, to remove double-stranded RNA (dsRNA), we use ribozymes - molecular scissors - to precisely cut the mRNA at its 3’ end. This assures not only 3’ homogeneity, but also eliminates dsRNA, which are primarily produced due to self-templated additions at the 3’ end. Utilizing a PCR-like system to amplify the DNA template in large quantities eliminates the requirement for plasmid enrichment in bacteria, the prime source of endotoxin contamination. These are just a few examples of Cisterna’s powerful technologies being used to achieve our goal of 10x higher quality mRNA for therapeutic application.

Cisterna Biologics의 YC 지원서, 재구성됨

Y Combinator 지원

Cisterna Biologics, Summer 2022 기수. 공개 데이터를 기반으로 작성된 실제 지원 질문.

Founders2
Company7
Progress7
Idea4
Equity3
Curious2
Batch Preference1

Company

Company name

Cisterna Biologics

Describe what your company does in 50 characters or less.

High quality mRNA for therapeutic use

What is your company going to make? Please describe your product and what it does or will do.

We make mRNA optimized for therapeutic use by solving challenges around quality, quantity, longevity, and cost. Our platform removes contaminants like double-stranded RNA using ribozymes to cut precisely at the mRNA 3' end, ensuring purity and consistency. We also replace bacterial plasmid amplification with a PCR-based system to eliminate endotoxin contamination and scale DNA templates efficiently. This leads to mRNA of substantially higher quality for drug developers tackling diseases amenable to mRNA therapy.

Where do you live now, and where would the company be based after YC?

We live and operate out of San Diego, CA, where the company is also based. After YC, we'd stay here to keep close ties to the biotech ecosystem and our team.

Explain your decision regarding location.

San Diego's biotech community suits our focus on synthetic biology and mRNA therapeutics. It has the scientific talent and lab access we need to keep pushing quality and manufacturing innovations. Relocating after YC would disrupt progress.

전체 지원서에서 21개의 추가 답변

Founders, Progress, Idea, Equity, Curious, Batch Preference는 전체 버전에 있습니다. 무료 계정을 만들어 YC Insights에서 모든 YC 배치 옆에 열어보세요.

전체 지원 보기

자주 묻는 질문

Cisterna Biologics의 실제 YC 지원서인가요?

아닙니다. Y Combinator는 제출된 지원서를 비공개로 유지합니다. 이것은 재구성된 것입니다. 실제 YC 양식 질문에 Cisterna Biologics의 공개 데이터(출시 노트, 창업자 배경, 제품 설명)를 기반으로 답변했습니다. Cisterna Biologics과 같은 회사가 YC에 어떻게 자신을 소개하는지 보여주며, 그들이 제출한 텍스트는 아닙니다.