Thesis YC Application

Fall 2025Active

Thesis went through Y Combinator in the Fall 2025 batch as a B2B company. Below: what the company does, who founded it, and its application to YC, reconstructed question by question in the real YC form.

YC batch: Fall 2025
Industry: B2B
Team size: 2
Status: Active
Launched: 2025

Founders

Sergio CharlesCo-Founder & CEO
Luigi CharlesFounder

What Thesis does

We are automating AI research and development. Our aim is to help AI researchers uncover the next AlphaFold or build the next Transformer, faster, more systematically, and at scale. We treat discovery not as a matter of luck, but as a combinatorial search problem. Every major breakthrough in AI over the next decade will be made by Thesis.

Thesis's YC application, reconstructed

Y Combinator application

Thesis, Fall 2025 batch. The real form questions, answered from public data.

Founders2
Company7
Progress7
Idea4
Equity3
Curious2
Batch Preference1

Company

Company name

Thesis

Describe what your company does in 50 characters or less.

Autonomous AI research

What is your company going to make? Please describe your product and what it does or will do.

We're building a platform that automates AI research and development. Our product treats discovery like a combinatorial search problem, helping AI researchers find breakthroughs faster and more systematically. Early users are AI labs and researchers who want to uncover the next big AI model or method without relying on luck or guesswork.

Where do you live now, and where would the company be based after YC?

We live in San Francisco, CA, and the company is based here and will remain based here after YC.

Explain your decision regarding location.

San Francisco is where we are now and it's the center of AI research and startups, giving us access to early partners and talent. Staying here after YC makes the most sense for building relationships and recruiting.

21 more answers in the full application

Founders, Progress, Idea, Equity, Curious, Batch Preference are in the full version. Create a free account to open it in YC Insights, next to every other YC batch.

See full application

Frequently Asked Questions

Is this the real Thesis YC application?

No. Y Combinator keeps submitted applications private. This is a reconstruction: the real YC form questions, answered from Thesis's public data (launch notes, founder backgrounds, product description). It shows how a company like Thesis would present itself to YC, not the text they submitted.