Matrubials

Matrubials YC Application

Summer 2021Active

Matrubials went through Y Combinator in the Summer 2021 batch as a Healthcare company. Below: what the company does, who founded it, and its application to YC, reconstructed question by question in the real YC form.

YC batch
Summer 2021
Industry
HealthcareDrug Discovery and Delivery
Team size
4
Status
Active
Launched
2021

Founders

  • Bruce German
    Bruce GermanFounder
  • Carlito Lebrilla
    Carlito LebrillaFounder
  • David Mills
    David MillsFounder

What Matrubials does

Matrubials is an anti-infectives company, focused on human milk peptides as therapeutics to address antimicrobial resistance and modern diseases. Currently the global rise in severe bacterial infections and the drying pipeline of effective treatments are burdensome for healthcare and economics. Sculpted by evolution, milk, first food for the newborn, provides an exemplary solution to address the nutritive and protective challenges an infant is faced with. The anti-pathogenic molecules from milk can be developed into therapeutics geared towards all-age diseases. Our first indication is bacterial vaginosis, a bacterial dysbiosis related inflammation that results in recurrent infections, disruption of homeostasis and long-term clinical complications in women of reproductive age, including but not limited to preterm births, fertility issues and increased rates of STDs. Our next inflection point is the evaluation of rapidly acting and selective candidate peptides in pre-clinical host impact and early safety studies, which can aid clinical and portfolio development towards topical applications.

Matrubials's YC application, reconstructed

Y Combinator application

Matrubials, Summer 2021 batch. The real form questions, answered from public data.

  1. Founders2
  2. Company7
  3. Progress7
  4. Idea4
  5. Equity3
  6. Curious2
  7. Batch Preference1

Company

Company name

Matrubials

Describe what your company does in 50 characters or less.

Milk-inspired therapeutics for infectious diseases

What is your company going to make? Please describe your product and what it does or will do.

We are developing antimicrobial peptides derived from human milk to treat bacterial infections. Our lead program targets bacterial vaginosis, aiming to restore microbial balance and prevent recurrent infections and inflammation that affect women's reproductive health. These peptides act selectively to avoid disrupting beneficial bacteria and offer a novel treatment approach against antimicrobial resistance.

Where do you live now, and where would the company be based after YC?

We live and work in Davis, CA. After YC, the company will remain based here to leverage local research connections and our core scientific team.

Explain your decision regarding location.

Davis hosts our founders and is near key research institutions. Staying here maintains continuity in science and development and supports our focused approach on milk-based therapeutics.

21 more answers in the full application

Founders, Progress, Idea, Equity, Curious, Batch Preference are in the full version. Create a free account to open it in YC Insights, next to every other YC batch.

Frequently Asked Questions

Is this the real Matrubials YC application?

No. Y Combinator keeps submitted applications private. This is a reconstruction: the real YC form questions, answered from Matrubials's public data (launch notes, founder backgrounds, product description). It shows how a company like Matrubials would present itself to YC, not the text they submitted.

What YC batch was Matrubials in?

Matrubials was part of the Y Combinator Summer 2021 batch.

Who founded Matrubials?

Matrubials was founded by Bruce German, Carlito Lebrilla, David Mills.

What does Matrubials do?

Developing milk-inspired therapeutics for infectious diseases

How do I read the full reconstructed application?

Create a free Round Funded account. The full 26-answer version of Matrubials's application, and every other YC batch, is in YC Insights.

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