Cisterna Biologics YC 申请

Summer 2022Active

Cisterna Biologics 在 Summer 2022 批次的 Y Combinator 中作为一家 Healthcare 公司进行过。以下是：公司做什么、谁创立了它，以及其 YC 申请，按照真实 YC 表格逐题重建。

YC 批次: Summer 2022
行业: Healthcare
团队规模: 2
状态: Active
已发布: 2022

创始人

Hari BhaskaranFounder

Cisterna Biologics 做什么

Founded in 2022 and based in San Diego, California, Cisterna Biologics is a technology company. It aims to solve some of the challenges currently facing the biotech industry to develop mRNA-based therapeutics - quality, quantity, longevity and cost of mRNA. As mRNA technology matures, it becomes imperative that these issues are solved so we can fully explore mRNA's endless possibilities as a therapeutic. Cisterna uses proprietary technologies to either remove a contaminant at its source or replace the source itself. For example, to remove double-stranded RNA (dsRNA), we use ribozymes - molecular scissors - to precisely cut the mRNA at its 3’ end. This assures not only 3’ homogeneity, but also eliminates dsRNA, which are primarily produced due to self-templated additions at the 3’ end. Utilizing a PCR-like system to amplify the DNA template in large quantities eliminates the requirement for plasmid enrichment in bacteria, the prime source of endotoxin contamination. These are just a few examples of Cisterna’s powerful technologies being used to achieve our goal of 10x higher quality mRNA for therapeutic application.

Cisterna Biologics 的 YC 申请，重建版

Y Combinator 申请

Cisterna Biologics，Summer 2022 期。来自公开数据的真实申请问题解答。

Founders2
Company7
Progress7
Idea4
Equity3
Curious2
Batch Preference1

Company

Company name

Cisterna Biologics

Describe what your company does in 50 characters or less.

High quality mRNA for therapeutic use

What is your company going to make? Please describe your product and what it does or will do.

We make mRNA optimized for therapeutic use by solving challenges around quality, quantity, longevity, and cost. Our platform removes contaminants like double-stranded RNA using ribozymes to cut precisely at the mRNA 3' end, ensuring purity and consistency. We also replace bacterial plasmid amplification with a PCR-based system to eliminate endotoxin contamination and scale DNA templates efficiently. This leads to mRNA of substantially higher quality for drug developers tackling diseases amenable to mRNA therapy.

Where do you live now, and where would the company be based after YC?

We live and operate out of San Diego, CA, where the company is also based. After YC, we'd stay here to keep close ties to the biotech ecosystem and our team.

Explain your decision regarding location.

San Diego's biotech community suits our focus on synthetic biology and mRNA therapeutics. It has the scientific talent and lab access we need to keep pushing quality and manufacturing innovations. Relocating after YC would disrupt progress.

21 更多回答在完整申请中

Founders, Progress, Idea, Equity, Curious, Batch Preference 包含在完整版中。创建免费账户即可在 YC Insights 中打开，紧邻每个其他 YC 批次。

查看完整申请

常见问题解答

这是 Cisterna Biologics 的真实 YC 申请吗？

不是。Y Combinator 对提交的申请保密。这是重建版：使用 Cisterna Biologics 的公开数据（发布笔记、创始人背景、产品描述）回答真实的 YC 表格问题。它展示了像 Cisterna Biologics 这样的公司会如何向 YC 自我介绍，而不是他们提交的文本。

Cisterna Biologics 是哪个 YC 批次的？

Cisterna Biologics 是 Y Combinator Summer 2022 批次的成员。

谁创立了 Cisterna Biologics？

Cisterna Biologics 由 Hari Bhaskaran 创立。

Cisterna Biologics 做什么？

High quality mRNA for therapeutic application

如何阅读完整的重建申请？

创建免费的 Round Funded 账户。YC Insights 中包含 Cisterna Biologics 的完整 26 个问题的版本，以及其他所有 YC 批次的公司信息。