Encepheal Therapeutics YC Başvurusu

Summer 2019Inactive

Encepheal Therapeutics, Healthcare şirketi olarak Summer 2019 grubunda Y Combinator'dan geçti. Aşağıda: şirketin ne yaptığı, kimin kurduğu ve gerçek YC formunda yeniden yapılandırılmış YC başvurusu.

YC grubu: Summer 2019
Sektör: HealthcareTherapeutics
Ekip büyüklüğü: 3
Durum: Inactive
Lansmanı Yapıldı: 2019

Kurucular

Aaron LazarusFounder
Omeed RahimiFounder

Encepheal Therapeutics ne yapar

EncepHeal is developing medications to treat substance abuse. Our first product is a small molecule therapeutic for stimulants like cocaine and methamphetamine, of which there are no FDA approved treatments. Our small molecule technology are atypical inhibitors of the dopamine transporter. Cocaine itself is an inhibitor of the same transporter. Directly reducing craving or positive reinforcement is a successful treatment strategy for addiction. Methadone or buprenorphine (Suboxone) are key examples of this for opioid use disorder. However, these types of medications can be addictive themselves. This has been a major hurdle for medication development for cocaine addiction and has led to many leaders in the addiction space to abandon the dopamine transporter as a target. At EncepHeal, we believe that the dopamine transporter should not be abandoned and instead focusing on fixing the abuse liability problem. Therefore with our partners at the National Institutes of Health, we have shown that these new, allosteric modulators at the dopamine transporter do not display addictive tendencies in animal models. They are also effective at curbing cocaine addiction. Our management team has two co-founders, Omeed Rahimi and Aaron Lazarus, as well as an experienced addiction pharmacologist as their research officer. The team has an advisory board with entrepreneurial and addiction drug development experience as well as expert partners at the National Institute on Drug Abuse, a subset of the NIH, and Wake Forest. Our team has had success in raising non-dilutive funding and has expertise with SBIR/STTR grants. We are looking for help in better connecting with the biotech/pharmaceutical industry.

Encepheal Therapeutics'in YC başvurusu, yeniden yapılandırılmış

Y Combinator başvurusu

Encepheal Therapeutics, Summer 2019 dönemi. Gerçek form soruları, herkese açık verilerden yanıtlandı.

Founders2
Company7
Progress7
Idea4
Equity3
Curious2
Batch Preference1

Company

Company name

Encepheal Therapeutics

Describe what your company does in 50 characters or less.

Medications to treat substance abuse

What is your company going to make? Please describe your product and what it does or will do.

We're developing small molecule drugs that target the dopamine transporter to treat stimulant addiction, starting with cocaine and methamphetamine. Our compounds modulate the dopamine transporter allosterically to reduce addictive cravings without the addictive properties of current dopamine transporter inhibitors.

Where do you live now, and where would the company be based after YC?

We currently live and work in Winston-Salem, NC, and the company is based there. After YC, we plan to maintain our base in Winston-Salem due to our partnerships and existing infrastructure.

Explain your decision regarding location.

We chose Winston-Salem because we have strong research collaborations with the National Institutes of Health and Wake Forest, which are local. This proximity helps us advance our drug development efficiently.

Tam başvuruda 21 ek cevap

Founders, Progress, Idea, Equity, Curious, Batch Preference tam sürümde. YC Insights'ta, diğer her YC grubu yanında açmak için ücretsiz bir hesap oluşturun.

Tüm başvuruyu gör

Sıkça Sorulan Sorular

Bu, Encepheal Therapeutics şirketinin gerçek YC başvurusu mu?

Hayır. Y Combinator gönderilen başvuruları gizli tutar. Bu bir yeniden yapılandırmadır: gerçek YC form soruları, Encepheal Therapeutics'in kamuya açık verilerinden (lansman notları, kurucu geçmişleri, ürün açıklaması) yanıtlanmıştır. Encepheal Therapeutics gibi bir şirketin YC'ye kendisini nasıl sunacağını gösterir, gönderdikleri metni değil.

Encepheal Therapeutics hangi YC grubundaydı?

Encepheal Therapeutics, Y Combinator Summer 2019 grubundaydı.

Encepheal Therapeutics kim tarafından kuruldu?

Encepheal Therapeutics, Aaron Lazarus, Omeed Rahimi tarafından kuruldu.

Encepheal Therapeutics ne iş yapar?

EncepHeal develops medications to treat substance abuse, starting…

Tam yeniden oluşturulmuş başvuruyu nasıl okurum?

Ücretsiz bir Round Funded hesabı oluşturun. Encepheal Therapeutics'ın başvurusunun tam 26 soruluk versiyonu ve diğer tüm YC batch'leri YC Insights'ta.