Inscrição YC de Cisterna Biologics
Cisterna Biologics passou pela Y Combinator no batch Summer 2022 como uma empresa Healthcare. Abaixo: o que a empresa faz, quem a fundou e sua inscrição para a YC, reconstruída pergunta por pergunta no formulário real da YC.
- Batch YC
- Summer 2022
- Indústria
- Healthcare
- Tamanho da equipe
- 2
- Status
- Active
- Lançada
- 2022
Fundadores
Hari BhaskaranFounder
O que Cisterna Biologics faz
Founded in 2022 and based in San Diego, California, Cisterna Biologics is a technology company. It aims to solve some of the challenges currently facing the biotech industry to develop mRNA-based therapeutics - quality, quantity, longevity and cost of mRNA. As mRNA technology matures, it becomes imperative that these issues are solved so we can fully explore mRNA's endless possibilities as a therapeutic. Cisterna uses proprietary technologies to either remove a contaminant at its source or replace the source itself. For example, to remove double-stranded RNA (dsRNA), we use ribozymes - molecular scissors - to precisely cut the mRNA at its 3’ end. This assures not only 3’ homogeneity, but also eliminates dsRNA, which are primarily produced due to self-templated additions at the 3’ end. Utilizing a PCR-like system to amplify the DNA template in large quantities eliminates the requirement for plasmid enrichment in bacteria, the prime source of endotoxin contamination. These are just a few examples of Cisterna’s powerful technologies being used to achieve our goal of 10x higher quality mRNA for therapeutic application.
Inscrição YC de Cisterna Biologics, reconstruída
Inscrição Y Combinator
Cisterna Biologics, lote Summer 2022. As verdadeiras perguntas do formulário, respondidas com dados públicos.
- Founders2
- Company7
- Progress7
- Idea4
- Equity3
- Curious2
- Batch Preference1
Company
Cisterna Biologics
High quality mRNA for therapeutic use
We make mRNA optimized for therapeutic use by solving challenges around quality, quantity, longevity, and cost. Our platform removes contaminants like double-stranded RNA using ribozymes to cut precisely at the mRNA 3' end, ensuring purity and consistency. We also replace bacterial plasmid amplification with a PCR-based system to eliminate endotoxin contamination and scale DNA templates efficiently. This leads to mRNA of substantially higher quality for drug developers tackling diseases amenable to mRNA therapy.
We live and operate out of San Diego, CA, where the company is also based. After YC, we'd stay here to keep close ties to the biotech ecosystem and our team.
San Diego's biotech community suits our focus on synthetic biology and mRNA therapeutics. It has the scientific talent and lab access we need to keep pushing quality and manufacturing innovations. Relocating after YC would disrupt progress.
21 respostas a mais na inscrição completa
Founders, Progress, Idea, Equity, Curious, Batch Preference estão na versão completa. Crie uma conta gratuita para abri-la no YC Insights, ao lado de todos os outros batches da YC.
Perguntas Frequentes
Esta é a inscrição real da YC de Cisterna Biologics?
Não. A Y Combinator mantém as inscrições submetidas em privado. Esta é uma reconstrução: as perguntas reais do formulário da YC, respondidas a partir dos dados públicos de Cisterna Biologics (notas de lançamento, históricos de fundadores, descrição do produto). Mostra como uma empresa como Cisterna Biologics se apresentaria à YC, não o texto que eles submeteram.
Em qual batch da YC Cisterna Biologics esteve?
Cisterna Biologics fez parte do batch Summer 2022 da Y Combinator.
Quem fundou o Cisterna Biologics?
O Cisterna Biologics foi fundado por Hari Bhaskaran.
O que o Cisterna Biologics faz?
High quality mRNA for therapeutic application
Como eu leio o application completo reconstruído?
Crie uma conta gratuita no Round Funded. A versão completa de 26 respostas do application do Cisterna Biologics, e de todos os outros lotes do YC, está no YC Insights.
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