Application YC di Cisterna Biologics
Cisterna Biologics ha partecipato a Y Combinator nel batch Summer 2022 come azienda Healthcare. Sotto: cosa fa l'azienda, chi l'ha fondata e la sua application a YC, ricostruita domanda per domanda nel form reale di YC.
- Batch YC
- Summer 2022
- Settore
- Healthcare
- Dimensione team
- 2
- Stato
- Active
- Lanciata
- 2022
Founder
Hari BhaskaranFounder
Cosa fa Cisterna Biologics
Founded in 2022 and based in San Diego, California, Cisterna Biologics is a technology company. It aims to solve some of the challenges currently facing the biotech industry to develop mRNA-based therapeutics - quality, quantity, longevity and cost of mRNA. As mRNA technology matures, it becomes imperative that these issues are solved so we can fully explore mRNA's endless possibilities as a therapeutic. Cisterna uses proprietary technologies to either remove a contaminant at its source or replace the source itself. For example, to remove double-stranded RNA (dsRNA), we use ribozymes - molecular scissors - to precisely cut the mRNA at its 3’ end. This assures not only 3’ homogeneity, but also eliminates dsRNA, which are primarily produced due to self-templated additions at the 3’ end. Utilizing a PCR-like system to amplify the DNA template in large quantities eliminates the requirement for plasmid enrichment in bacteria, the prime source of endotoxin contamination. These are just a few examples of Cisterna’s powerful technologies being used to achieve our goal of 10x higher quality mRNA for therapeutic application.
Application YC di Cisterna Biologics, ricostruita
Domanda per Y Combinator
Cisterna Biologics, batch Summer 2022. Le vere domande del form, risposte da dati pubblici.
- Founders2
- Company7
- Progress7
- Idea4
- Equity3
- Curious2
- Batch Preference1
Company
Cisterna Biologics
High quality mRNA for therapeutic use
We make mRNA optimized for therapeutic use by solving challenges around quality, quantity, longevity, and cost. Our platform removes contaminants like double-stranded RNA using ribozymes to cut precisely at the mRNA 3' end, ensuring purity and consistency. We also replace bacterial plasmid amplification with a PCR-based system to eliminate endotoxin contamination and scale DNA templates efficiently. This leads to mRNA of substantially higher quality for drug developers tackling diseases amenable to mRNA therapy.
We live and operate out of San Diego, CA, where the company is also based. After YC, we'd stay here to keep close ties to the biotech ecosystem and our team.
San Diego's biotech community suits our focus on synthetic biology and mRNA therapeutics. It has the scientific talent and lab access we need to keep pushing quality and manufacturing innovations. Relocating after YC would disrupt progress.
21 risposte in più nell'application completa
Founders, Progress, Idea, Equity, Curious, Batch Preference sono nella versione completa. Crea un account gratuito per aprirla in YC Insights, accanto a ogni altro batch YC.
Domande Frequenti
Questa è l'application YC reale di Cisterna Biologics?
No. Y Combinator mantiene private le application inviate. Questa è una ricostruzione: le domande del form YC reale, a cui si è risposto usando i dati pubblici di Cisterna Biologics (note di lancio, background dei founder, descrizione del prodotto). Mostra come un'azienda come Cisterna Biologics si presenterebbe a YC, non il testo che hanno inviato.
A quale batch YC apparteneva Cisterna Biologics?
Cisterna Biologics apparteneva al batch Summer 2022 di Y Combinator.
Chi ha fondato Cisterna Biologics?
Cisterna Biologics è stato fondato da Hari Bhaskaran.
Cosa fa Cisterna Biologics?
High quality mRNA for therapeutic application
Come leggo la ricostruzione completa della application?
Crea un account Round Funded gratuito. La versione completa di 26 risposte della application di Cisterna Biologics, e di ogni altro batch YC, è in YC Insights.
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