Nucleo YC Application

Fall 2025Active

Nucleo went through Y Combinator in the Fall 2025 batch as a Healthcare company. Below: what the company does, who founded it, and its application to YC, reconstructed question by question in the real YC form.

YC batch: Fall 2025
Industry: Healthcare
Team size: 2
Status: Active
Launched: 2025

Founders

Angelica IacovelliFounder
Luca PegolottiFounder

What Nucleo does

We help oncologists and radiologists extract insights from CT scans to support tumor characterization and treatment. The hospitals we work with include Stanford Hospital, Cedars-Sinai, UCI Health, and Weill Cornell.

Nucleo's YC application, reconstructed

Y Combinator application

Nucleo, Fall 2025 batch. The real form questions, answered from public data.

Founders2
Company7
Progress7
Idea4
Equity3
Curious2
Batch Preference1

Company

Company name

Nucleo

Describe what your company does in 50 characters or less.

The first Agentic platform for Oncology

What is your company going to make? Please describe your product and what it does or will do.

We build a platform that helps oncologists and radiologists extract insights from CT scans to characterize tumors and guide treatment decisions. Our tools process imaging data and provide interpretable analyses tailored to oncology use cases.

Where do you live now, and where would the company be based after YC?

We and the company are currently remote.

Explain your decision regarding location.

We are remote because our team is small and our work is software-based, allowing us to collaborate effectively without a fixed location. This also helps us stay flexible while working with hospitals across the U.S.

21 more answers in the full application

Founders, Progress, Idea, Equity, Curious, Batch Preference are in the full version. Create a free account to open it in YC Insights, next to every other YC batch.

See full application

Frequently Asked Questions

Is this the real Nucleo YC application?

No. Y Combinator keeps submitted applications private. This is a reconstruction: the real YC form questions, answered from Nucleo's public data (launch notes, founder backgrounds, product description). It shows how a company like Nucleo would present itself to YC, not the text they submitted.