Cisterna Biologics YC-Bewerbung

Summer 2022Active

Cisterna Biologics durchlief Y Combinator im Summer 2022-Batch als ein Healthcare-Unternehmen. Unten: Was das Unternehmen tut, wer es gegründet hat und seine Bewerbung bei YC, Frage für Frage im echten YC-Formular rekonstruiert.

YC-Batch: Summer 2022
Branche: Healthcare
Teamgröße: 2
Status: Active
Gestartet: 2022

Gründer

Hari BhaskaranFounder

Was Cisterna Biologics tut

Founded in 2022 and based in San Diego, California, Cisterna Biologics is a technology company. It aims to solve some of the challenges currently facing the biotech industry to develop mRNA-based therapeutics - quality, quantity, longevity and cost of mRNA. As mRNA technology matures, it becomes imperative that these issues are solved so we can fully explore mRNA's endless possibilities as a therapeutic. Cisterna uses proprietary technologies to either remove a contaminant at its source or replace the source itself. For example, to remove double-stranded RNA (dsRNA), we use ribozymes - molecular scissors - to precisely cut the mRNA at its 3’ end. This assures not only 3’ homogeneity, but also eliminates dsRNA, which are primarily produced due to self-templated additions at the 3’ end. Utilizing a PCR-like system to amplify the DNA template in large quantities eliminates the requirement for plasmid enrichment in bacteria, the prime source of endotoxin contamination. These are just a few examples of Cisterna’s powerful technologies being used to achieve our goal of 10x higher quality mRNA for therapeutic application.

Cisterna Biologicss YC-Bewerbung, rekonstruiert

Y Combinator Bewerbung

Cisterna Biologics, Summer 2022 Batch. Die echten Fragen des Antrags, beantwortet aus öffentlichen Daten.

Founders2
Company7
Progress7
Idea4
Equity3
Curious2
Batch Preference1

Company

Company name

Cisterna Biologics

Describe what your company does in 50 characters or less.

High quality mRNA for therapeutic use

What is your company going to make? Please describe your product and what it does or will do.

We make mRNA optimized for therapeutic use by solving challenges around quality, quantity, longevity, and cost. Our platform removes contaminants like double-stranded RNA using ribozymes to cut precisely at the mRNA 3' end, ensuring purity and consistency. We also replace bacterial plasmid amplification with a PCR-based system to eliminate endotoxin contamination and scale DNA templates efficiently. This leads to mRNA of substantially higher quality for drug developers tackling diseases amenable to mRNA therapy.

Where do you live now, and where would the company be based after YC?

We live and operate out of San Diego, CA, where the company is also based. After YC, we'd stay here to keep close ties to the biotech ecosystem and our team.

Explain your decision regarding location.

San Diego's biotech community suits our focus on synthetic biology and mRNA therapeutics. It has the scientific talent and lab access we need to keep pushing quality and manufacturing innovations. Relocating after YC would disrupt progress.

21 weitere Antworten in der vollständigen Bewerbung

Founders, Progress, Idea, Equity, Curious, Batch Preference sind in der Vollversion. Erstelle ein kostenloses Konto, um es in YC Insights neben jedem anderen YC-Batch zu öffnen.

Vollständige Bewerbung anzeigen

Häufig gestellte Fragen

Ist das die echte YC-Bewerbung von Cisterna Biologics?

Nein. Y Combinator hält eingereichte Bewerbungen privat. Dies ist eine Rekonstruktion: die echten Fragen des YC-Formulars, beantwortet aus den öffentlichen Daten von Cisterna Biologics (Veröffentlichungsnotizen, Gründerhintergründe, Produktbeschreibung). Sie zeigt, wie sich ein Unternehmen wie Cisterna Biologics bei YC präsentieren würde, nicht den Text, den sie eingereicht haben.

In welchem YC-Batch war Cisterna Biologics?

Cisterna Biologics war Teil des Y Combinator Summer 2022-Batches.

Wer hat Cisterna Biologics gegründet?

Cisterna Biologics wurde von Hari Bhaskaran gegründet.

Was macht Cisterna Biologics?

High quality mRNA for therapeutic application

Wie lese ich die vollständige, rekonstruierte Bewerbung?

Erstelle ein kostenloses Round Funded Konto. Die vollständige 26-Antwort-Version der Bewerbung von Cisterna Biologics, und jede andere YC-Kohorte, findest du in YC Insights.